Description
Product Overview
Vasoactive Intestinal Peptide (VIP) is a premium-quality synthetic 28-amino acid neuropeptide manufactured exclusively for laboratory and scientific research. Naturally produced throughout the gastrointestinal tract, central nervous system, and immune system, VIP functions as an important biological signaling molecule involved in numerous physiological processes.
Extensive research has demonstrated that Vasoactive Intestinal Peptide (VIP) regulates inflammatory signaling, promotes vascular relaxation, maintains epithelial barrier integrity, influences neurotransmission, and contributes to circadian rhythm regulation. These diverse biological activities make VIP an essential research peptide across immunology, neuroscience, pulmonary medicine, gastrointestinal biology, and cardiovascular research.
Manufactured using advanced Solid-Phase Peptide Synthesis (SPPS), each production batch undergoes stringent purification by High-Performance Liquid Chromatography (HPLC) and verification through Mass Spectrometry (MS) to ensure exceptional purity, identity, and batch-to-batch consistency.
Peptide Overview
Vasoactive Intestinal Peptide belongs to the glucagon-secretin peptide family and functions primarily as a non-adrenergic, non-cholinergic neurotransmitter.
Its biological effects are mediated through activation of two G-protein coupled receptors:
• VPAC1
• VPAC2
Binding to these receptors stimulates adenylate cyclase activity, increasing intracellular cyclic adenosine monophosphate (cAMP). This signaling pathway regulates numerous biological functions, including:
• Immune cell communication
• Smooth muscle relaxation
• Vasodilation
• Mucosal protection
• Neurotransmission
• Hormonal regulation
• Circadian rhythm signaling
Because of its broad physiological activity, VIP continues to receive considerable attention in translational biomedical research.
Research Grade Manufacturing
Every batch of Vasoactive Intestinal Peptide (VIP) is manufactured under strict quality standards using advanced peptide synthesis technology.
Our quality control process includes:
✔️ Advanced Solid-Phase Peptide Synthesis (SPPS)
✔️ Reverse-Phase HPLC purification
✔️ Mass Spectrometry identity confirmation
✔️ Individual batch quality testing
✔️ High purity (≥98%)
✔️ Excellent batch consistency
Quality Assurance
Each production batch is carefully tested to ensure:
• High chemical purity
• Correct molecular identity
• Low residual solvent levels
• Minimal trifluoroacetic acid (TFA) residue
• Endotoxin-controlled manufacturing
• Excellent stability for laboratory research
Laboratory Research Applications
Vasoactive Intestinal Peptide (VIP) is widely investigated in multiple scientific disciplines.
Immunology & Inflammation
Researchers investigate VIP for its ability to regulate immune responses through modulation of cytokine production, including reduced expression of TNF-α, IL-6, and IFN-γ while promoting anti-inflammatory mediators such as IL-10.
Cardiovascular & Pulmonary Research
VIP has been extensively studied for its potent vasodilatory effects and ability to relax vascular smooth muscle. Current investigations include pulmonary arterial pressure regulation and vascular function.
Neuroscience & Neuroprotection
Ongoing studies examine VIP’s role in:
• Neuroinflammation
• Neuronal survival
• Synaptic signaling
• Neurodegenerative disease models
• Brain immune regulation
Gastrointestinal Research
VIP plays an important role in gastrointestinal physiology.
Research areas include:
• Intestinal epithelial barrier integrity
• Tight junction regulation
• Gastric motility
• Intestinal secretion
• Gut immune homeostasis
Cell Signaling Research
VIP continues to be investigated for its involvement in:
• cAMP signaling
• GPCR activation
• Cellular communication
• Endocrine regulation
• Signal transduction pathways
Handling & Reconstitution
For optimal stability:
1. Briefly centrifuge the vial before opening.
2. Reconstitute using sterile deionized water or phosphate-buffered saline (PBS).
3. If necessary, use a minimal amount of sterile 1% acetic acid to improve solubility.
4. Gently swirl until completely dissolved.
5. Avoid vigorous vortexing or repeated agitation.
Following reconstitution, prepare single-use aliquots whenever possible to minimize degradation caused by repeated freeze-thaw cycles.
Storage Recommendations
Lyophilized Powder
Store at -20°C in a dry, light-protected environment. Under proper storage conditions, the peptide remains stable for up to 24 months.
Reconstituted Solution
Store at 2–8°C if used within seven days.
For extended preservation, divide into aliquots and store at -80°C. Avoid repeated freeze-thaw cycles to maintain peptide integrity.
Why Choose Our Vasoactive Intestinal Peptide (VIP)?
• Premium Research Grade
• ≥98% HPLC Verified Purity
• Mass Spectrometry Confirmed
• Manufactured Using Advanced SPPS Technology
• Excellent Batch-to-Batch Consistency
• Endotoxin-Controlled Production
• Fast Dissolution
Secure Packaging
• Ideal for In Vitro and In Vivo Research
Disclaimer
This product is supplied exclusively for laboratory research and scientific investigation. It is not intended for human consumption, clinical application, therapeutic use, diagnostic procedures, or veterinary use. Purchasers are responsible for ensuring compliance with all applicable laws, regulations, and institutional guidelines governing the handling and use of research materials.
Reviews
There are no reviews yet.