Description

What is 5-Amino-1MQ?

5-Amino-1MQ (5-Amino-1-methylquinolinium) is a selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). Although commonly found within peptide research catalogs because of its relevance to metabolic and longevity studies, it is chemically classified as a synthetic small molecule rather than a peptide.

NNMT plays an important role in regulating cellular methylation and energy metabolism. Elevated NNMT activity has been associated with altered metabolic function, reduced cellular energy expenditure, and age-related physiological changes. By selectively inhibiting this enzyme, 5-Amino-1MQ enables researchers to investigate pathways involved in mitochondrial function, NAD+ metabolism, lipid utilization, and muscle biology

Research Applications

Current preclinical research has identified 5-Amino-1MQ as a valuable research tool across multiple scientific disciplines.

Adipocyte Metabolism

Researchers investigate 5-Amino-1MQ for its potential influence on fat cell metabolism and lipid oxidation pathways. Experimental models suggest NNMT inhibition may alter cellular energy utilization without directly affecting food intake.

NAD+ Metabolism

NNMT inhibition may increase intracellular nicotinamide availability for NAD+ biosynthesis, making 5-Amino-1MQ an important compound for studying cellular energy regulation and metabolic homeostasis.

Mitochondrial Function

Studies evaluate how modulation of NNMT influences mitochondrial efficiency, ATP production, and cellular energy metabolism.

Healthy Aging Research

Researchers use 5-Amino-1MQ to explore mechanisms associated with longevity-related pathways, including activation of SIRT1, cellular maintenance, and age-associated metabolic changes.

Muscle Physiology

Preclinical investigations continue to evaluate the role of NNMT inhibition in skeletal muscle regeneration, muscle stem cell function, and age-related muscle decline.

Key Features

• Research-grade 5-Amino-1MQ

• ≥99% purity verified by HPLC

• Identity confirmed by Mass Spectrometry (MS)

• Selective NNMT inhibitor

• High laboratory consistency

• Excellent chemical stability

• Suitable for metabolic and longevity research

• Manufactured under strict quality control standards

• Intended exclusively for laboratory research

Quality Assurance

Every batch of 5-Amino-1MQ undergoes comprehensive quality testing to ensure exceptional research performance.

Purity Verification

Each lot is analyzed using:

• High-Performance Liquid Chromatography (HPLC)

• Mass Spectrometry (MS)
to verify a chemical purity of 99% or greater.

Contaminant Screening

Our material is tested to ensure it is free from:

• Heavy metals

• Structural fillers

• Pyrogens

Unwanted contaminants
helping researchers achieve reliable and reproducible experimental results.

Storage & Handling

To maintain maximum stability:

• Store in a cool, dry location.

• Protect from moisture and direct sunlight.

• Long-term storage is recommended at −20°C.

• Keep containers tightly sealed after use.

Solubility

5-Amino-1MQ demonstrates good laboratory solubility in:

• Dimethyl Sulfoxide (DMSO)

• Appropriate aqueous laboratory buffers

Researchers should optimize solvent selection according to individual experimental protocols.

Laboratory Research Use Only

Important Notice

This product is supplied exclusively as a research chemical.

It is intended only for:

• Laboratory research

• In vitro experiments

• Approved animal research

This product is not intended for:

• Human consumption

• Veterinary use

• Therapeutic applications

• Diagnostic procedures

• Recreational use

Why Choose Our 5-Amino-1MQ?

Researchers require products that deliver both quality and consistency. Our 5-Amino-1MQ is manufactured to rigorous laboratory standards, tested for purity using validated analytical methods, and supplied for advanced metabolic, mitochondrial, and longevity research. Every batch is produced to support reproducible scientific investigations with dependable quality.

Research Use Disclaimer

5-Amino-1MQ is supplied exclusively as a research chemical for laboratory and scientific investigation.
This product is intended for research use only and is not intended for human or veterinary use. It is not approved by regulatory authorities for the diagnosis, treatment, cure, or prevention of any disease.

This product must only be handled by qualified researchers and trained laboratory personnel operating in appropriately equipped research facilities. Any experimental use should comply with all applicable local, national, and institutional regulations.

By purchasing this product, the purchaser acknowledges that they understand the intended research-only purpose of 5-Amino-1MQ and agrees that it will not be used for human consumption, clinical applications, food or dietary supplementation, cosmetic use, recreational purposes, or any unlawful activity.
The purchaser assumes full responsibility for the safe handling, storage, transportation, and disposal of this research chemical. The manufacturer and seller accept no liability for misuse, improper handling, or use of this product outside its intended laboratory research applications.